Diagnostic accuracy of saline hysterosonography in cases of abnormal uterine bleeding

To evaluate diagnostic accuracy of saline hysterosonography in diagnosing endometrial hyperplasia taking histopathology as gold standard. Validation study. Radiology Department MH/CMH Rawalpindi form 10th July 2006 to 10th January 2007. Fifty cases of Abnormal Uterine Bleeding comprising both pre and post menopausal patients were included. They were selected on non probability convenience sampling technique. Saline hysterosonography was conducted in the Radiology Department and results compared with histopathological findings. Among 50 patients who underwent saline hysterosonography, 40 patients were diagnosed to have positive findings while 10 did not show any abnormality on saline hysterosonography. Of the 10 patients whose endometrium did not show any abnormality on saline hysterosonography, 8 were found to be normal on histopathology and 2 cases showed abnormality. One case was of endometrial hyperplasia and the other showed a benign endocervical polyp which was missed on saline hysterosonography. This showed that Saline hysterosonography has a sensitivity of 94.7%, specificity of 66.7%, and an overall diagnostic accuracy of 88%. Saline hysterosonography is highly accurate in the diagnosis of endometrial pathologies. It is cost effective, well tolerated by patients and can be performed as an outpatient procedure

Validity of colour doppler ultrasonography with d-dimers in clinically suspected deep venous thrombosis of the lower LIMB

This study was designed to evaluate the validity of colour Doppler ultrasonography with D-dimers in clinically suspected deep venous thrombosis of the lower limb. Validation study Place and Duration of study: Radiology Department CMH/MH Rawalpindi Six months from 15 June 2006 to 31 December 2006. Subjects and Thirty cases of clinically suspected deep venous thrombosis of the lower limb were included in the study selected on non probability convenience sampling technique. Colour Doppler ultrasonography examination of the affected lower limb was carried out and results compared with D-dimers assays results. Among 30 patients who underwent colour Doppler ultrasonography examination of the affected limb for diagnosis of deep venous thrombosis, 27 [90%] were diagnosed to have deep venous thrombosis, 3 [10%] were diagnosed not to have deep venous thrombosis. Amongst them 2 patients had raised D-dimers levels and repeat Doppler ultrasound advised. On revised ultrasound deep venous thrombosis in these patients was confirmed. This showed that colour Doppler ultrasonography examination has sensitivity of 93.1%, specificity 100%, positive predictive value 100%, negative predictive value 33.33% and overall accuracy of 93.33%. Colour Doppler ultrasonography has a high diagnostic yield in cases of deep venous thrombosis of lower limb when used in conjunction with D-dimers assays